The Nobel Prize in Medicine for 2025 has been awarded to Mary E Brunkow, Fred Ramsdell, and Shimon Sakaguchi for groundbreaking discoveries concerning the human immune system that prevents it from harming the body.
The Nobel Prize in Medicine for 2025 has been awarded to Mary E Brunkow, Fred Ramsdell, and Shimon Sakaguchi for their work on immune system.
The Nobel committee said that the human body’s powerful immune system must be regulated, or it may attack own organs, and Brunkow, Ramsdell, and Sakaguchi made groundbreaking discoveries that prevent the immune system from harming the body.
They identified the immune system’s security guards, regulatory T cells, which prevent immune cells from attacking own body, and their discoveries launched the field of peripheral tolerance, spurring the development of medical treatments for cancer and autoimmune diseases, the statement read.
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This may also lead to more successful transplantations and several of these treatments are now undergoing clinical trials, the statement read.
Who are Nobel Prize winners in Medicine for 2025?
Sakaguchi is a 74-year-old Japanese immunologist, Brunkow is a 64-year-old American molecular biologist, and Ramsdell is a 65-year-old American immunologist.
In 1995, Sakaguchi made the key discovery about T cells. At the ti