A new blood test can detect more than 50 types of cancer, as well as where in the body they originated — even before symptoms develop.
Researchers in the United States and United Kingdom developed the new test, and they now report their findings in the journal Annals of Oncology.
There is an urgent need for better diagnostic tools for cancer. All too often, healthcare professionals can only make a diagnosis after symptoms have developed — at which point it may be too late for curative treatment.
Screening programs, such as mammograms for breast cancer and Pap smears for cervical cancer, intend to overcome this problem by detecting cancer at an earlier stage.
However, these tests are typically only available to a subset of the population (those at highest risk), are limited to a small number of cancers, and have variable rates of compliance. These methods can also be invasive or uncomfortable, which may discourage attendance.
Now, researchers have developed a simple blood test that can detect over 50 different types of cancer, in many cases before any clinical signs or symptoms develop, from just a single draw of blood.
The test works using a type of DNA released by tumor cells. This sheds into the blood, where it is known as cell-free DNA (cfDNA). It can be challenging to identify tumor-specific cfDNA, however, because many other cells also release DNA into the blood.
This test detects DNA that is specifically from cancer cells using changes to the DNA — namely, the addition of a chemica