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University of Queensland-led research study reveals being obese can hinder the body’s antibody reaction to SARS-CoV-2 infection however not to the defense provided by vaccination.
Research study lead, School of Chemistry and Molecular Biosciences Ph.D. prospect Marcus Tong, stated the finding constructed on the group’s existing research study on how COVID-19 impacts individuals who are obese. The research study is released in Medical & & Translational Immunology
“We’ve formerly revealed that being obese– not simply being overweight– increases the seriousness of SARS-CoV-2,” Mr. Tong stated.
“But this work reveals that being obese develops an impaired antibody reaction to SARS-CoV-2 infection however not to vaccination.”
The research study group gathered blood samples from individuals who had actually recuperated from COVID-19 and not been reinfected throughout the research study duration, roughly 3 months and 13 months post-infection.
“At 3 months post-infection, a raised BMI was connected with decreased antibody levels,” Mr. Tong stated.
“And at 13 months post-infection, a raised BMI was connected with both decreased antibody activity and a minimized portion of the pertinent B cells, a kind of cell that assists develop these COVID-fighting antibodies.”
On the other hand, a raised BMI had no impact on the antibody action to COVID-19 v