— Preterm, COVID-exposed babies with breathing distress had actually marked inflammatory reactions
by Katherine Kahn, Staff Writer, MedPage Today
January 24, 2024
Babies born to unvaccinated moms who had COVID-19 throughout pregnancy were at high danger for establishing neonatal breathing distress, the longitudinal, associate COMP research study discovered.
The chances of establishing breathing distress were threefold greater (OR 3.06, 95% CI 1.08-10.21) in babies born to unvaccinated moms detected with COVID-19 while pregnant compared to COVID-exposed babies born to COVID-vaccinated moms, Mary Catherine Cambou, MD, of the University of California Los Angeles (UCLA), and associates reported in Nature Communications.
“This was not something we were anticipating to see, as none of the infants were detected with COVID-19 themselves,” co-author Karin Nielsen-Saines, MD, likewise from UCLA, informed MedPage Today in an e-mail. “We likewise kept in mind that breathing distress was not short-term and lasted a number of days.”
When pregnant individuals had actually gotten at least one mRNA vaccine dosage prior to SARS-CoV-2 infection, the chances of their babies establishing neonatal breathing distress dropped to 0.33 (95% CI 0.10-0.96)– a 67% decrease, the authors pointed out.
Maternal COVID-19 illness seriousness likewise seemed related to the occurrence of neonatal breathing distress. Thirteen percent of pregnancies satisfied requirements for extreme or important COVID-19. Amongst babies with breathing distress, 21% were born to moms with extreme or important COVID-19, while just 6% of children without breathing distress were born to females with serious illness (P=0.009).
Around 56% of babies with breathing distress were either late preterm or term shipments and 44% were preterm. “We were shocked to discover