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April 26, 2024– Before there wasOzempicWegovy, or Zepbound, there were cost-friendly, safe, and efficient weight-loss drugs. FDA-approved weight problems medication like orlistat (brand:Xenicalphentermine/topiramate (Qsymiaand naltrexone/bupropion extended release (Contravehave actually been on the marketplace for years.
“Some older weight problems medications go all the method back to the ’50s and ’60s– like phentermine, which is still among the most commonly recommended medications on the planet,” stated Anthony Auriemma, MD, medical director of Ascension Illinois Weight Loss Solutions.
While more recent GLP-1 drugs likesemaglutide (Ozempic,Wegovytypically cause higher degrees of weight reduction, the advantages of more recognized drugs– like lower expenses, sufficient supply, and ease of gain access to– likewise makes them important choices, stated Andres Acosta, MD, a weight problems specialist with the Mayo Clinic.
“Many individuals state that the GLP-1s are the very first medications to offer you weight reduction at double digits,” he stated. “That is not real. Qsymia was currently at double digits, offering you 11% [of total body weight loss] at the medium dosage and 13% at the high dosage.”
And 2 cost-friendly and efficient drugs provide lower degrees of weight reduction: Contrave (around 9%) and Xenical (5% to 6%).
Some clients can get drugmaker vouchers for Qsymia and Contrave for as low as $100 monthly, and generic phentermine as low as $20 each month, Auriemma stated. You can discover Xenical for $200 to $300 each month. Compare these expenses to GLP-1s, like Ozempic, where you are paying out a minimum of $500, all the method as much as countless dollars, monthly.
An independentevaluation by the Institute for Clinical and Economic Review discovered that Qsymia is the most affordable me