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Findings from a brand-new mouse research study recommend that elenolic acid, a natural substance discovered in olives, can reduce blood sugar level levels and promote weight-loss. The research study might lead the way to the advancement of safe and affordable natural items for handling weight problems and type 2 diabetes in individuals.
The scientists discovered that after simply one week, overweight mice with diabetes that were offered oral elenolic acid weighed considerably less and revealed much better blood sugar level (glucose) guideline than before treatment and compared to manage overweight mice not getting elenolic acid. The glucose-lowering result was equivalent with that of the injectable diabetic medication liraglutide and much better than metformin, among the most typical oral medications for type 2 diabetes.
“Lifestyle adjustments and public health steps have actually had minimal effect on the increasing frequency of weight problems, among the leading threat aspects for type 2 diabetes,” stated research study group leader Dongmin Liu, Ph.D., a teacher in the Department of Human Nutrition, Foods and Exercise at Virginia Tech.
“Available weight problems drugs are inadequate in weight-loss upkeep, pricey and/or bring possible long-lasting security threats. Our objective was to establish more secure, less expensive and easier multi-targeting representatives that can avoid the incident of metabolic conditions and type 2 diabetes.”
Hana Alkhalidy, Ph.D., a research study researcher in Liu’s laboratory at Virginia Tech, provides the findings at NUTRITION 2024, the flagship yearly conference of the American Society for Nutrition held June 29– July 2 in Chicago.
Liu’s research study group concentrates on finding bioactive substances from natural items for diabetes management. Formerly, they searched for particular molecular targets for natural substances in parts of the body that actively assist manage