A delivery rider has died and another has been injured after being stabbed by a man allegedly tampering with their bikes.
The two riders, both men, confronted the man on Frederick Way in Melbourne’s CBD before he allegedly stabbed one multiple times and the other once just before 8.10pm on Friday.
WATCH THE VIDEO ABOVE: Fatal stabbing in Melbourne CBD sparks major manhunt
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Emergency services raced to the scene and performed CPR on the rider with multiple wounds, but the yet-to-be-identified man died at the scene, police said.
The second rider, aged in his 30s, was located nearby and was taken to hospital with non-life-threatening injuries.
A witness told 7NEWS the man who lost his life was delivery rider for food delivery service Hungry Panda.
“The (alleged) assaulter grabbed a knife and (he) was stabbed is his chest and unfortunately … he passed away,” he said.
Emergency services at the scene of the suspected stabbing. Credit: Supplied Other Hungry Panda riders chased the suspect into a nearby bus station to try and apprehend him, the witness added.
“They failed because he’s still grabbing this knife,” he said.
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“He ran away along this sidewalk … his clothes had a lot of blood.”
A crime scene was established, shutting down the area between Queen St and A’Beckett St while homicide detectives began their investigation and began searching for the suspect.
Images from the scene show emergency service cordons and crowds standing around police tape.
Police on Friday morning confirmed a 51-year-old man was arrested in Footscray in relation to the incident.
No arrests have been made. Credit: Supplied “He remains in custody and will be interviewed,” Police said.
“Police are not looking for anyone else in relation to the incident.”
Investigations remain ongoing and anyone with information has been urged to contact Crime Stoppers.